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Hochdurchsatzsequenzierung /cfDNA in Tiermodellen

Comparative High-Resolution Transcriptome Sequencing of Lymphoma Cell Lines and de novo Lymphomas Reveals Cell-Line-Specific Pathway Dysregulation.

Taher L, Beck J, Liu W, Roolf C, Soller JT, Rütgen BC, Hammer SE, Chodisetti M, Sender S, Sterenczak KA, Fuellen G, Junghanss C, Brenig B, Nolte I, Schütz E, Murua Escobar H.

Sci Rep. 2018; 19;8(1): 6279. doi: 10.1038/s41598-018-23207-7

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Optimized expression-based microdissection of formalin-fixed lung cancer tissue.

Grafen M, Hofmann TR, Scheel AH, Beck J, Emmert A, Küffer S, Danner BC, Schütz E, Büttner R, Ostendorf A, Ströbel P, Bohnenberger H.

Lab Invest. 2017; 97: 863-872. doi: 10.1038/labinvest.2017.31.

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Characterization of the novel indolylmaleimides' PDA-66 and PDA-377 effect on canine lymphoma cells.

Liu W, Beck J, Schmidt LC, Roolf C, Pews-Davtyan A, Rütgen BC, Hammer S, Willenbrock S, Sekora A, Rolfs A, Beller M, Brenig B, Nolte I, Junghanss C, Schütz E, Murua Escobar H.

Oncotarget. 2016 Jun 7;7(23):35379-89. doi: 10.18632/oncotarget.9297.

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Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing
miR-146a in Acute Myeloid Leukemia.

Mohr S, Doebele C, Comoglio F, Berg T, Beck J, Bohnenberger H, Alexe G, Corso J, Ströbel P, Wachter A, Beissbarth T, Schnütgen F, Cremer A, Haetscher N, Göllner S, Rouhi A, Plamqvist L, Rieger MA, Schroeder T, Bönig H, Müller-Tidow C, Kuchenbauer, F, Schütz E, Green AR, Urlaub H, Stegmaier K, Humphries RK, Serve H, Oellerich T.

Published. April 10, 2017. doi: 10.1016/j.ccell.2017.03.001

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Prevalence of the Prefoldin Subunit 5 Gene Deletion in Canine Mammary Tumors.

Hennecke S, Beck J, Bornemann-Kolatzki K, Neumann S, Murua Escobar H, Nolte I, Hammer SC, Hewicker-Trautwein M, Junginger J, Kaup FJ, Brenig B, Schütz E.

PLoS One. 2015 Jul 1;10(7):e0131280. doi: 10.1371/journal.pone.0131280.

PMID: 26132936

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FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation.

Oellerich T, Mohr S, Corso J, Beck J, Döbele C, Braun H, Cremer A, Münch S, Wicht J, Oellerich MF, Bug G, Bohnenberger H, Perske C, Schütz E, Urlaub H, Serve H.

Blood. 2015 Mar 19;125(12):1936-47. doi: 10.1182/blood-2014-06-585216.

PMID: 25605370

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Analysis of circulating DNA distribution in pregnant and nonpregnant dairy cows.

Mayer J, Beck J, Soller JT, Wemheuer W, Schütz E, Brenig B.

Biol Reprod. 2013 Feb 7;88(2):29. doi: 10.1095/biolreprod.112.103168.

PMID: 23255334

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Genome aberrations in canine mammary carcinomas and their detection in cell-free plasma DNA.

Beck J, Hennecke S, Bornemann-Kolatzki K, Urnovitz HB, Neumann S, Ströbel P, Kaup FJ, Brenig B, Schütz E.

PLoS One. 2013 Sep 30;8(9):e75485. doi: 10.1371/journal.pone.0075485.

PMID: 24098698

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Serum DNA motifs predict disease and clinical status in multiple sclerosis.

Beck J, Urnovitz HB, Saresella M, Caputo D, Clerici M, Mitchell WM, Schütz E.

J Mol Diagn. 2010 May;12(3):312-9. doi: 10.2353/jmoldx.2010.090170.

PMID: 20228264

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Disease-specific motifs can be identified in circulating nucleic acids from live elk and cattle infected with transmissible spongiform encephalopathies.

Gordon PM, Schütz E, Beck J, Urnovitz HB, Graham C, Clark R, Dudas S, Czub S, Sensen M, Brenig B, Groschup MH, Church RB, Sensen CW.

Nucleic Acids Res. 2009 Feb;37(2):550-6. doi: 10.1093/nar/gkn963.

PMID: 19059996

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Serum nucleic acids in an experimental bovine transmissible spongiform encephalopathy model.

Beck J, Urnovitz HB, Groschup MH, Ziegler U, Brenig B, Schütz E.

Zoonoses Public Health. 2009 Aug;56(6-7):384-90. doi: 10.1111/j.1863-2378.2009.01260.x.

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Bov-tA short interspersed nucleotide element sequences in circulating nucleic acids from sera of cattle with bovine spongiform encephalopathy (BSE) and sera of cattle exposed to BSE.

Schütz E, Urnovitz HB, Iakoubov L, Schulz-Schaeffer W, Wemheuer W, Brenig B.

Clin Diagn Lab Immunol. 2005 Jul;12(7):814-20.

PMID: 16002628

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