Publikationen zum Thema Transplantation

Donor-Derived Cell-Free DNA Testing in Solid Organ Transplantation: A Value Proposition

Oellerich M, Christenson RH, Beck J, Schütz E, Sherwood K, Price CP, Keown PA, Walson PD

The Journal of Applied Laboratory Medicine, Volume 5, Issue 5, September 2020, Pages 993–1004.  doi:10.1093/jalm/jfaa062

Liquid biopsies: donor-derived cell-free DNA for the detection of kidney allograft injury

Oellerich M, Sherwood K, Keown P, Schütz E, Beck J, Stegbauer J, Rump LC, Walson PD

Nature Reviews Nephrology volume 17, pages 591–603 (2021). doi:10.1038/s41581-021-00428-0.

Graft-Derived Cell-Free DNA as a Noninvasive Biomarker of Cardiac Allograft Rejection: a Cohort Study on Clinical Validity and Confounding Factors

Knüttgen F, Beck J, Dittrich M, Oellerich M, Zittermann A, Schulz U, Fuchs U, Knabbe C, Schütz E, Gummert J, Birschmann I

J Clin Med. 2021 Jan 7;10(2):193. doi: 10.3390/jcm10020193. PMID: 33430458

Time-Dependent Apparent Increase in dd-cfDNA Percentage in Clinically Stable Patients Between One and Five Years Following Kidney Transplantation

Schütz E, Asendorf T, Beck J, Schauerte V, Mettenmeyer N, Shipkova M, Wieland E, Kabakchiev M, Walson PD, Schwenger V, Oellerich M

Clinical Chemistry, Volume 66, Issue 10, October 2020, Pages 1290–1299. doi: 10.1093/clinchem/hvaa175

A Universal Droplet Digital PCR Approach for Monitoring of Graft Health After Transplantation Using a Preselected SNP Set.

Beck J, Oellerich M, Schütz E.

Methods Mol Biol. 2018; 1768: 335-348. doi: 10.1007/978-1-4939-7778-9_19.

Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study.

Schütz E, Fischer A, Beck J, Harden M, Koch M, Wuensch T, Stockmann M, Nashan B, Kollmar O, Matthaei J, Kanzow P, Walson PD, Brockmöller J, Oellerich M.

PLoS Med (2017) 14: e1002286. doi:10.1371/journal.pmed.1002286

Graft-Derived Cell-Free DNA as a Marker of Transplant Graft Injury.

Oellerich M, Walson PD, Beck J, Schmitz J, Kollmar O, Schütz E.

Ther Drug Monit. 2016 Apr;38 Suppl 1:S75-9. doi: 10.1097/FTD.0000000000000239. Review.

PMID: 26418703

Donor-Derived Cell-Free DNA Is a Novel Universal Biomarker for Allograft Rejection in Solid Organ Transplantation.

Beck J, Oellerich M, Schulz U, Schauerte V, Reinhard L, Fuchs U, Knabbe C, Zittermann A, Olbricht C, Gummert JF, Shipkova M, Birschmann I, Wieland E, Schütz E.

Transplant Proc. 2015 Oct;47(8):2400-3. doi: 10.1016/j.transproceed.2015.08.035.

PMID: 26518940

Graft-derived cell-free DNA as an early organ integrity biomarker after transplantation of a marginal HELLP syndrome donor liver.

Kanzow P, Kollmar O, Schütz E, Oellerich M, Schmitz J, Beck J, Walson PD, Slotta JE.

Transplantation. 2014 Sep 15;98(5):e43-5. doi: 10.1097/TP.0000000000000303.

PMID: 25171533

Use of graft-derived cell-free DNA as an organ integrity biomarker to reexamine effective tacrolimus trough concentrations after liver transplantation.

Oellerich M, Schütz E, Kanzow P, Schmitz J, Beck J, Kollmar O, Streit F, Walson PD.

Ther Drug Monit. 2014 Apr;36(2):136-40. doi: 10.1097/FTD.0000000000000044.

PMID: 24452066

Digital droplet PCR for rapid quantification of donor DNA in the circulation of transplant recipients as a potential universal biomarker of graft injury.

Beck J, Bierau S, Balzer S, Andag R, Kanzow P, Schmitz J, Gaedcke J, Moerer O, Slotta JE, Walson P, Kollmar O, Oellerich M, Schütz E.

Clin Chem. 2013 Dec;59(12):1732-41. doi: 10.1373/clinchem.2013.210328.

PMID: 24061615

Absolute quantification of donor‐derived cell‐free DNA as a marker of rejection and graft injury in kidney transplantation: Results from a prospective observational study

Michael Oellerich, Maria Shipkova, Thomas Asendorf, Philip D. Walson, Verena Schauerte, Nina Mettenmeyer, Mariana Kabakchiev, Georg Hasche, Hermann-Josef Gröne, Tim Friede, Eberhard Wieland, Vedat Schwenger, Ekkehard Schütz, Julia Beck

2019 The Authors. American Journal of Transplantation published by Wiley Periodicals, Inc. on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons.

doi.org/10.1111/ajt.15416